LeBron James, who netted 31 points against the Nuggets, has scored 32,311 points, surpassing Jordan’s tally of 32,292.
He achieved the feat in 1,190 games, compared to Michael Jordan’s 1,072.
“I don’t know, man, a lot of the stuff I’ve done in my career, this ranks right at the top,” the 34-year-old said after the game.
“For a kid from Akron, Ohio, that needed inspiration, needed some type of positive influence, MJ was that guy for me.
“I wanted to be like MJ, wanted to shoot fadeaways like MJ, wanted to stick my tongue out on dunks like MJ, wanted to wear my sneakers like MJ. I wanted kids to look up to me at some point like MJ.
“It’s crazy, to be honest. It’s beyond crazy.”
Only Kareem Abdul-Jabbar, Karl Malone and Kobe Bryant have scored more points than LeBron James, who began his NBA career with Cleveland Cavaliers in 2003.
The Ohio-born player joined Miami Heat in 2010, returning to the Cavs four years later before switching to the Lakers last July in a four-year deal worth $154m (£116m).
LeBron James appeared to send a message to Michael Jordan with “thank you MJ” written on his shoe. Last month LeBron James became the first player to move on to the NBA’s top 10 all-time scoring and assists lists.
He has won three NBA titles – twice with Heat in 2012 and 2013, along with another with the Cavs in 2016, appeared in the past eight NBA Finals and has been named the league’s most valuable player on four occasions.